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產(chǎn)品概述
| 名稱 | AsPC-1 (人轉(zhuǎn)移胰腺腺癌細胞) (STR鑒定正確) |
| 別稱 | AsPc-1; Aspc-1; ASPC-1; As-PC1; ASPC1; AsPC1; Aspc1; AsPc1 |
| 種屬 | 人 |
| 生長特性 | 貼壁細胞 |
| 細胞形態(tài) | 上皮細胞樣 |
| 凍存條件 | 凍存液：55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度：液氮 |
| 培養(yǎng)方案A（默認） |
培養(yǎng)條件:
氣相：空氣，95%；CO2，5%, 溫度：37℃
|
| 推薦傳代比例 | 1:3-1:4 |
| 推薦換液頻率 | 2-3次/周 |
| 背景描述 | AsPC-1細胞來源于人胰腺癌病人腹水中的細胞裸鼠異種移植而產(chǎn)生的癌性腹水細胞；AsPC-1細胞可以表達CEA、人胰腺相關(guān)抗原、人胰腺特異性抗原和黏蛋白。 |
| 年齡（性別） | 女性；62歲 |
| 組織來源 | 胰腺；轉(zhuǎn)移灶；腹水腺癌 |
| 細胞類型 | 腫瘤細胞 |
| 腫瘤類型 | 胰腺癌細胞 |
| 生物安全等級 | BSL-1 |
| 倍增時間 | ~38-48 hours |
| 基因表達情況 | carcinoembryonic antigen (CEA); human pancreas associated antigen; human pancreas specific antigen; mucin |
| 保藏機構(gòu) | ATCC; CRL-1682 BCRC; 60494 ECACC; 96020930 |
STR鑒定
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STR位點信息
Amelogenin X CSF1PO 10,13 D2S1338 22,23 D3S1358 16 D5S818 12 D7S820 12,13 D8S1179 13,15 D13S317 9,12 D16S539 11 D18S51 18 D19S433 14 D21S11 28,30 FGA 24 PentaD 9,12 PentaE 5,12 TH01 7,9.3 TPOX 8,10 vWA 17 D6S1043 11,20 D12S391 19 D2S441 11,14 -
STR鑒定圖
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參考文獻
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D3S-001, a KRAS G12C inhibitor with rapid target engagement kinetics, overcomes nucleotide cycling and demonstrates robust preclinical and clinical activities(2024/05/08)
作者：Jing Zhang, Sunmin Lim, Mira Yu
期刊：Cancer Discovery
DOI：10.1158/2159-8290.CD-24-0006
影響因子 ：28.200
引用產(chǎn)品：CL-0027
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ZMAT1 acts as a tumor suppressor in pancreatic ductal adenocarcinoma by inducing SIRT3/p53 signaling pathway(2022/04/07)
作者：Ma Zuyi, Li Zhenchong, Wang Shujie
期刊：JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
DOI：10.1186/s13046-022-02310-8
影響因子 ：11.300
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Albumin binding revitalizes NQO1 bioactivatable drugs as novel therapeutics for pancreatic cancer(2022/08/04)
作者：Lei Dou, Huiqin Liu, Kaixin Wang
期刊：JOURNAL OF CONTROLLED RELEASE
DOI：10.1016/j.jconrel.2022.07.033
影響因子 ：10.800
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Concurrent inhibition of pBADS99 synergistically improves MEK inhibitor efficacy in KRASG12D-mutant pancreatic ductal adenocarcinoma(2024/02/26)
作者：Yanqin Tan, Bowen Sun, Xi Zhang
期刊：Cell Death & Disease
DOI：10.1038/s41419-024-06551-7
影響因子 ：9.000
引用產(chǎn)品：CL-0027
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Upstream stimulatory factor 2 inhibits erastin-induced ferroptosis in pancreatic cancer through transcriptional regulation of pyruvate kinase M2(2022/09/20)
作者：Meijie Chen, Xuena Li, Bulin Du
期刊：BIOCHEMICAL PHARMACOLOGY
影響因子 ：5.800
引用產(chǎn)品：CL-0027 CL-0042 CL-0059 CL-0184 CL-0448 CL-0627 CM-0059 CM-0448A
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5′-tRF-19-Q1Q89PJZ Suppresses the Proliferation and Metastasis of Pancreatic Cancer Cells via Regulating Hexokinase 1-Mediated Glycolysis(2023/10/12)
作者：Wenpeng Cao, Zhirui Zeng, Shan Lei
期刊：Biomolecules
影響因子 ：5.500
引用產(chǎn)品：CL-0027
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LINC00909 up-regulates pluripotency factors and promotes cancer stemness and metastasis in pancreatic ductal adenocarcinoma by targeting SMAD4(2024/03/19)
作者：Zhenchong Li, Zuyi Ma, Shujie Wang
期刊：Biology Direct
DOI：10.1186/s13062-024-00463-4
影響因子 ：5.500
引用產(chǎn)品：CL-0027
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Pancreatic stellate cell-derived exosomal tRF-19-PNR8YPJZ promotes proliferation and mobility of pancreatic cancer through AXIN2(2023/07/24)
作者：Wenpeng Cao, Shisi Dai, Wanyuan Ruan
期刊：JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
影響因子 ：5.300
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COL12A1 Acts as a Novel Prognosis Biomarker and Activates Cancer-Associated Fibroblasts in Pancreatic Cancer through Bioinformatics and Experimental Validation(2023/02/26)
作者：Yao Song, Lei Wang, Kaidong Wang
期刊：Cancers
影響因子 ：5.200
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KIF2C Facilitates Tumor Growth and Metastasis in Pancreatic Ductal Adenocarcinoma(2023/02/27)
作者：Xing Huang, Feng Zhao, Quan Wu
期刊：Cancers
影響因子 ：5.200
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Novel PORCN inhibitor WHN-88 targets Wnt/β-catenin pathway and prevents the growth of Wnt-driven cancers(2023/02/28)
作者：Qihong Yang, Tong Qin, Tao An
期刊：EUROPEAN JOURNAL OF PHARMACOLOGY
DOI：10.1016/j.ejphar.2023.175628
影響因子 ：5.000
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MiR-24-3p Inhibits the Progression of Pancreatic Ductal Adenocarcinoma Through LAMB3 Downregulation(2020/01/21)
作者：Wenjie Huang, Jianyou Gu, Tian Tao
期刊：Frontiers in Oncology
影響因子 ：4.700
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GPR120 promotes metastasis but inhibits tumor growth in pancreatic ductal adenocarcinoma(2022/06/05)
作者：Xiaoyuan Sun, Huijun Chu, Ke Lei
期刊：PANCREATOLOGY
影響因子 ：3.977
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Lactobacillus casei combined with Lactobacillus reuteri alleviate pancreatic cancer by inhibiting TLR4 to promote macrophage M1 polarization and regulate gut microbial homeostasis(2023/10/30)
作者：Zemin Zhu, Bo Yi, Zikai Tang
期刊：BMC CANCER
DOI：10.1186/s12885-023-11557-z
影響因子 ：3.800
引用產(chǎn)品：CL-0027
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An endoplasmic reticulum stress-related signature could robustly predict prognosis and closely associate with response to immunotherapy in pancreatic ductal adenocarcinoma(2023/08/31)
作者：Shuguang Liu, Qianying Hu, Zishan Xie
期刊：JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
DOI：10.1007/s00432-023-05312-x
影響因子 ：3.600
引用產(chǎn)品：CL-0027
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Long non-coding RNA OIP5-AS1 promotes pancreatic cancer cell growth through sponging miR-342-3p via AKT/ERK signaling pathway(2020/3/10)
作者：Xiangpeng Meng, Jia Ma, Baosheng Wang
期刊：Journal Of Physiology And Biochemistry
DOI：10.1007/s13105-020-00734-4
影響因子 ：3.400
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FAM53B promotes pancreatic ductal adenocarcinoma metastasis by regulating macrophage M2 polarization(2024/04/15)
作者：Xuanzeng Pei, Min Cai, Dawei Jiang
期刊：World Journal of Gastrointestinal Oncology
影響因子 ：3.000
引用產(chǎn)品：CL-0027
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Targeting the EZH2-PPAR Axis Is a Potential Therapeutic Pathway for Pancreatic Cancer(2021/7/22)
作者：Jilong Hu, Zhinan Zheng, Jia Lei
期刊：PPAR Research
影響因子 ：2.900
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Comprehensive pan-cancer analysis of role of GPRASP1, associated with clinical outcomes, immune microenvironment, and immunotherapeutic efficiency in pancreatic cancer(2023/02/12)
作者：Jiaxing Du, Yongsheng Chen, Genglong Liu
期刊：PATHOLOGY RESEARCH AND PRACTICE
影響因子 ：2.800
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miR-23a-5p inhibits cell proliferation and invasion in pancreatic ductal adenocarcinoma by suppressing ECM1 expression(2019/5/15)
作者：Wenjie Huang, Yaohuan Huang, Jianyou Gu
期刊：American Journal of Translational Research
DOI：PMID:31217868
影響因子 ：2.200
引用產(chǎn)品：CL-0027
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ZKSCAN5 activates LAPTM5 expression by recruiting SETD7 to promote metastasis in pancreatic ductal adenocarcinoma.(2023/11/22)
作者：Yong Yang , Wei Xie, Xuan Qiao
期刊：HISTOLOGY AND HISTOPATHOLOGY
影響因子 ：2.000
引用產(chǎn)品：CL-0027
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Knockdown of interferon-induced transmembrane protein 1 inhibited proliferation, induced cell cycle arrest and apoptosis, and suppressed MAPK signaling pathway in pancreatic cancer cells(2020/5/20)
作者：Lei Zhang, Zhenyong Wang, Deshuai Kong
期刊：Bioscience Biotechnology And Biochemistry
DOI：10.1080/09168451.2020.1762479
影響因子 ：1.600
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