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產(chǎn)品概述
| 名稱 | ARPE-19 (人視網(wǎng)膜上皮細胞) (STR鑒定正確) |
| 別稱 | ARPE19; Adult Retinal Pigment Epithelial cell line-19; NTC-200; NTC200 |
| 種屬 | 人 |
| 生長特性 | 貼壁細胞 |
| 細胞形態(tài) | 上皮細胞樣 |
| 凍存條件 | 凍存液：55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度：液氮 |
| 培養(yǎng)方案A（默認） |
培養(yǎng)條件:
氣相：空氣，95%；CO2，5%, 溫度：37℃
|
| 推薦傳代比例 | 1:3-1:4 |
| 推薦換液頻率 | 2-3次/周 |
| 年齡（性別） | 男性；19歲 |
| 組織來源 | 眼睛，視網(wǎng)膜 |
| 細胞類型 | 自發(fā)永生化細胞 |
| 生物安全等級 | BSL-1 |
| 倍增時間 | ~55-65 hours |
| 基因表達情況 | RPE-specific markers CRALBP and RPE-65 |
| 保藏機構(gòu) | ATCC; CRL-2302 BCRC; 60383 BCRJ; 0041 |
STR鑒定
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STR位點信息
Amelogenin X,Y CSF1PO 11 D2S1338 19 D3S1358 14,15 D5S818 13 D7S820 9,11 D8S1179 13 D13S317 11,12 D16S539 9,11 D18S51 12,16 D19S433 12,13 D21S11 28,29 FGA 23 PentaD 11,13 PentaE 7,11 TH01 6,9.3 TPOX 9,11 vWA 16,19 D6S1043 17,19 D12S391 21,22 D2S441 10,15 -
STR鑒定圖
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參考文獻
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Extracellular vesicles from organoid-derived human retinal progenitor cells prevent lipid overload-induced retinal pigment epithelium injury by regulating fatty acid metabolism(2023/12/27)
作者：Hui Gao, Yuxiao Zeng, Xiaona Huang
期刊：Journal of Extracellular Vesicles
影響因子 ：16.000
引用產(chǎn)品：CL-0026
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Aligned Nanofibers from Polypyrrole/Graphene as Electrodes for Regeneration of Optic Nerve via Electrical Stimulation(2016/03/09)
作者：Lu Yan, Bingxin Zhao, Xiaohong Liu
期刊：ACS Applied Materials & Interfaces
影響因子 ：9.500
引用產(chǎn)品：CL-0026
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PTK6 inhibits autophagy to promote uveal melanoma tumorigenesis by binding to SOCS3 and regulating mTOR phosphorylation(2023/01/23)
作者：Bo Liu, Xueting Yao, Chaoyang Zhang
期刊：Cell Death & Disease
DOI：10.1038/s41419-023-05590-w
影響因子 ：9.000
引用產(chǎn)品：CL-0026
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MiR-195 inhibits the ubiquitination and degradation of YY1 by Smurf2, and induces EMT and cell permeability of retinal pigment epithelial cells(2021/07/15)
作者：Shuhua Fu, Meichen Lai, Yunyao Zheng
期刊：Cell Death & Disease
DOI：10.1038/s41419-021-03956-6
影響因子 ：9.000
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Development of Uveal Melanoma-Specific Aptamer for Potential Biomarker Discovery and Targeted Drug Delivery(2023/02/22)
作者：Zhaoqi Pan, Hui Zhu, Yibin Zhang
期刊：Analytical Chemistry
DOI：10.1021/acs.analchem.3c00005
影響因子 ：7.400
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Identification of a novel immune-related gene signature for prognosis and the tumor microenvironment in patients with uveal melanoma combining single-cell and bulk sequencing data(2023/01/30)
作者：Wanpeng Wang, Han Zhao, Sha Wang
期刊：Frontiers in Immunology
DOI：10.3389/fimmu.2023.1099071
影響因子 ：7.300
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Asiatic acid attenuates diabetic retinopathy through TLR4/MyD88/NF-κB p65 mediated modulation of microglia polarization(2021/05/06)
作者：Mengyuan Fang,?Wencui Wan,?Qiuming Li
期刊：Life Sciences
影響因子 ：6.780
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ERp29 Attenuates Nicotine-Induced Endoplasmic Reticulum Stress and Inhibits Choroidal Neovascularization(2023/10/24)
作者：Tu Lu, Fangfang Xie, Chuangxin Huang
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影響因子 ：5.600
引用產(chǎn)品：CL-0026
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Astragaloside-IV alleviates high glucose-induced ferroptosis in retinal pigment epithelial cells by disrupting the expression of miR-138-5p/Sirt1/Nrf2(2022/03/18)
作者：Xuyuan Tang, Xiuyi Li, Dongyan Zhang
期刊：Bioengineered
DOI：10.1080/21655979.2022.2049471
影響因子 ：4.900
引用產(chǎn)品：CL-0026
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CYTOR-NFAT1 feedback loop regulates epithelial-mesenchymal transition of retinal pigment epithelial cells(2024/05/14)
作者：Rong Zhang, Lin Wang, Yang Li
期刊：Human Cell
DOI：10.1007/s13577-024-01075-w
影響因子 ：4.300
引用產(chǎn)品：CL-0026
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Diabetes and high-glucose could upregulate the expression of receptor for activated C kinase 1 in retina(2024/03/15)
作者：Jian Tan, Ang Xiao, Lin Yang
期刊：World Journal of Diabetes
影響因子 ：4.200
引用產(chǎn)品：CL-0026
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Gambogic acid ameliorates high glucose– and palmitic acid–induced inflammatory response in ARPE-19 cells via activating Nrf2 signaling pathway: ex vivo(2020/11/27)
作者：Jun Chen, Lihua Li, Yun Zhou
期刊：Cell Stress & Chaperones
DOI：10.1007/s12192-020-01182-1
影響因子 ：3.800
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Exome sequencing reveals PPEF2 variant associated with high myopia(2023/12/16)
作者：Sili Jing, Xianglong Yi
期刊：GENE
DOI：10.1016/j.gene.2023.148091
影響因子 ：3.500
引用產(chǎn)品：CL-0026
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Long non?coding RNA MALAT1 is involved in retinal pigment epithelial cell damage caused by high glucose treatment(2022/03/21)
作者：Xinli Jiang, Yan Liu, Yuling Wang
期刊：Molecular Medicine Reports
影響因子 ：3.423
引用產(chǎn)品：CL-0026
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GBP2 inhibits pathological angiogenesis in the retina via the AKT/mTOR/VEGFA axis(2024/04/16)
作者：Xiaoxiang Xu, Xihui Ding, Zizhuo Wang
期刊：MICROVASCULAR RESEARCH
影響因子 ：3.100
引用產(chǎn)品：CL-0026
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Hsa_circ_0000527 Downregulation Suppresses the Development of Retinoblastoma by Modulating the miR-27a-3p/HDAC9 Pathway(2021/11/25)
作者：Xiangrong Zuo, Changjiang Fu, Jing Xie
期刊：Current Eye Research
DOI：10.1080/02713683.2021.1925697
影響因子 ：2.000
引用產(chǎn)品：CL-0026
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Fetuin-B Overexpression Promotes Inflammation in Diabetic Retinopathy Through Activating Microglia and the NF-κB Signaling Pathway(2023/10/26)
作者：Wenyi Zhang, Jing Yao, Chen Chen
期刊：CURRENT EYE RESEARCH
DOI：10.1080/02713683.2023.2276683
影響因子 ：2.000
引用產(chǎn)品：CL-0026
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Autophagy: a new mechanism for regulating VEGF and PEDF expression in retinal pigment epithelium cells(2019/4/18)
作者：Rong Li, Junhui Du, Guomin Yao
期刊：International Journal of Ophthalmology
影響因子 ：1.400
引用產(chǎn)品：CL-0026
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All-trans retinoic acid regulates the expression of MMP-2 and TGF-β2 via RDH5 in retinal pigment epithelium cells(2023/06/18)
作者：Yumei Mao, Changjun Lan, Qingqing Tan
期刊：International Journal of Ophthalmology
影響因子 ：1.400
引用產(chǎn)品：CL-0026
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Autophagy dysregulation mediates the damage of high glucose to retinal pigment epithelium cells(2021/6/18)
作者：Qian Zhang, Hongsong Li, Rong Li
期刊：International Journal of Ophthalmology
影響因子 ：1.400
引用產(chǎn)品：CL-0026
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Fundus-Vascular Responses to Color Deviation Caused by Non-Oxidative Blue Filtering(2022/10/12)
作者：Jianqi Cai, Wentao Hao, Shanshan Zeng
期刊：Oxidative Medicine and Cellular Longevity
影響因子 ：0.000
引用產(chǎn)品：CL-0026
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GSDME Increases Chemotherapeutic Drug Sensitivity by Inducing Pyroptosis in Retinoblastoma Cells(2022/03/29)
作者： Fang Li, Qinyun Xia, Lian Ren
期刊：Oxidative Medicine and Cellular Longevity
影響因子 ：0.000
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